Hemp compounds stop coronavirus from entering human cells I CR News

A new research has shown that hemp compounds are capable of stopping coronavirus from entering human cells. The study by Oregon State University identified a few hemp compounds via a chemical screening technique invented at the university. The2 findings of the study have been published in Journal of Natural Products.

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Hemp, known scientifically as Cannabis sativa, is a source of fiber, food and animal feed, and multiple hemp extracts and compounds are added to cosmetics, body lotions, dietary supplements and food. Researchers found that a pair of cannabinoid acids bind to the SARS-CoV-2 spike protein, blocking a critical step in the process the virus uses to infect people.

Hemp compounds stop coronavirus from entering human cells I CR News 3

The compounds are cannabigerolic acid, or CBGA, and cannabidiolic acid, CBDA, and the spike protein is the same drug target used in COVID-19 vaccines and antibody therapy. A drug target is any molecule critical to the process a disease follows, meaning its disruption can thwart infection or disease progression. Those two variants are also known the alpha and beta variant, respectively.

Characterized by crown-like protrusions on its outer surface, SARS-CoV-2 features RNA strands that encode its four main structural proteins – spike, envelope, membrane and nucleocapsid – as well as 16 nonstructural proteins and several “accessory” proteins.

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Using compounds that block virus-receptor interaction has been helpful for patients with other viral infections including HIV-1 and hepatitis.

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